科研之友
微信
新浪微博
Facebook
分享链接
摘要
Background and objective: To combine the diagnosis of OSA with titration of positive airway pressure (PAP), current guidelines recommend that split-night polysomnography (PSG) be performed if an AHI of >= 40/h is recorded over 2 h. However, the diagnostic validity of partial-night PSG is uncertain. This study aimed to test the validity of partial-night PSG and to determine the optimum AHI cut-off points. Methods: Patients who visited the sleep centre at a tertiary medical centre between January and December 2008, for symptoms related to sleep disorders (sleepiness, snoring, sleep disturbance), and who completed full-night PSG, were evaluated for this study. Full-night PSG data were processed to obtain partial-night PSG data, from which AHI were computed as a reference for diagnosing severe OSA. Full-night and partial-night PSG data obtained over different recording times (expressed as x-h PSG, where x = 1-6) were compared using receiver operating characteristic (ROC) curve analysis. The diagnostic validity of 2-h PSG with different AHI cut-off points (25/h to 45/h) was also calculated. Results: Data from 198 PSG recordings was processed. For 2-h PSG, an AHI cut-off point of 30/h gave the highest accuracy of 90.9%. Comparing areas under the ROC curves (AUC), 2-h PSG (AUC = 0.97) was as good as 2.5-h PSG (AUC = 0.977, P = 0.057) and 3-h PSG (AUC = 0.978, P = 0.125), but was better than 1.5-h PSG (AUC = 0.955, P = 0.016). Conclusions: Partial-night PSG is effective for diagnosing severe OSA. If there is an unabridged PSG recording indicating an AHI of >= 30/h for 2 h, severe OSA can be diagnosed and PAP titration initiated.
- 出版日期2011-10
