A Facile and Efficient Oxalyldihydrazide/Ketone-Promoted Copper-Catalyzed Amination of Aryl Halides in Water

作者：Zhu, Xinhai; Su, Li; Huang, Liye; Chen, Gong; Wang, Jinlong; Song, Huacan; Wanlal, Yiqian^*

来源：European Journal of Organic Chemistry, 2009, (5): 635-642.

DOI：10.1002/ejoc.200800940

• Amination
• Cross-coupling
• Copper
• Water chemistry
• Sustainable chemistry

A novel three-component catalyst CuO/oxalyldihydrazide/hexane-2,5-dione was a very convenient, economic, and effective catalytic system for the Ullmann-type C-N coupling reaction in water. Both aryl bromides and aryl iodides could be aminated by a variety of amines even at room temperature or with heating to afford very good isolated yields.

• 出版日期2009-2
• 单位中山大学