Multiple Xanthogranulomas in an Adult: Known Entity, New Association

作者:Vadeboncoeur Sophie*; Provost Nathalie
来源:Journal of Cutaneous Medicine and Surgery, 2016, 20(5): 474-477.
DOI:10.1177/1203475416640795

摘要

Background: Multiple xanthogranulomas (XGs) in adults are rare, although an increasing number of case reports are being published. The most frequent association is hematologic malignancies, but the majority of cases remain idiopathic, with occasional spontaneous resolution. Objective: The aims of this report are to describe a case of eruptive XG in a woman with a solid neoplasia who was receiving imatinib and to review the literature. Methods and Results: This 33-year-old woman had a gastrointestinal stromal tumor. After undergoing surgical removal and being on imatinib for 1 year, the patient developed multiple slightly erythematous papules with an orange hue on the axillary region, trunk, abdomen, and thighs. A biopsy confirmed the diagnosis of XG. Conclusion: This is to the investigators' knowledge the first case of eruptive XG in the setting of a solid neoplasia. The possibility of drug-induced XG lesions due to imatinib cannot be excluded. This presentation could be added to the list of associations of adult XG.

  • 出版日期2016-9