A simple B-1 correction method for dynamic contrast-enhanced MRI

作者：Li, Z. F.; Zhao, W.; Qi, T. F.; Gao, C.; Gu, Q.; Zhao, J. S.; Koh, T. S.^*

来源：Physics in Medicine and Biology, 2018, 63(16): 16NTO1.

DOI：10.1088/1361-6560/aad519

• radiofrequency field B-1 inhomogeneity correction
• T-1 mapping
• variable flip angle method
• dynamic contrast-enhanced MRI

The double-angle method (DAM) is commonly used as a reference standard in radiofrequency field (B-1) mapping studies. This study explored two aspects of DAM: (i) use of small flip angle pairs to reduce the repetition time (TR) needed for adequate longitudinal relaxation (T-1); and (ii) the effect of using different flip angle ratios for B-1 mapping. Results of phantom studies show that B-1 correction using small flip angle pairs <= 60 degrees with TR = 5000 ms can allow for accurate estimation of T-1 up to about 1500 ms; and that increasing the ratio of the two flip angles used for B-1 correction resulted in more accurate estimation of T-1. These modifications allow 3-dimensional (3D) B-1 mapping to be consistently performed with the same 3D spoiled gradient echo sequence used for T-1 mapping in dynamic contrast-enhanced MRI.

• 出版日期2018-8
• 单位昆明医科大学