New trends in nuclear data research for medical radionuclide production

作者：Qaim S M^*

来源：Radiochimica Acta, 2013, 101(8): 473-480.

DOI：10.1524/ract.2013.2069

• Medical radionuclide
• Optimisation of production route
• Nuclear reaction cross section
• Standardisation of data
• Alternative routes for production of Tc-99m and Ga-68
• Non-standard positron emitter
• Novel therapeutic radionuclide

Nuclear reaction cross section data are of great significance in optimisation of production routes of radionuclides. This article deals with some newer aspects of data research related to production of both standard and novel radionuclides. The recent work to standardise the known data is discussed and new measurements with regard to further optimisation of production routes of some commonly used radionuclides are mentioned. Attempts to increase the specific activity of some reactor-produced radionuclides through the use of charged-particle induced reactions are outlined. The jeopardy in the supply of Tc-99m via a fission-produced Mo-99/Tc-99m generator is considered and its possible direct production at a cyclotron is briefly discussed. Regarding the novel radionuclides, development work is presently focussed on non-standard positron emitters for diagnosis and on low-range highly ionising radiation emitters for internal radiotherapy. Recent nuclear reaction cross section measurements related to the production of the two types of radionuclides are briefly reviewed and some anticipated trends in nuclear data research are considered.

• 出版日期2013