A Novel Enzymatic Synthesis of Quinoline Derivatives

作者：Zheng, Hui^*; Liu, Juan; Mei, Yi Jia; Shi, Qiao Yue; Zhang, Peng Fei

来源：Catalysis Letters, 2012, 142(5): 573-577.

DOI：10.1007/s10562-012-0774-8

• Enzymatic catalysis
• Heterocycles
• Cyclization
• Condensation

A new mild enzymatic methodology for synthesizing quinoline derivatives by Friedlander condensation was developed. A series of quinoline derivatives were synthesized and characterized by H-1 NMR, C-13-NMR, IR and MS. The probable enzymatic mechanism was proposed. It provides a novel method to prepare quinoline derivatives.

• 出版日期2012-5
• 单位杭州师范大学