Neural crest induction at the neural plate border in vertebrates

作者：Milet Cecile; Monsoro Burq Anne H^*

来源：Developmental Biology, 2012, 366(1): 22-33.

DOI：10.1016/j.ydbio.2012.01.013

• Neural crest
• Neural plate border
• AP2a
• Pax3
• Zic1
• Hairy2
• Msx1
• Xenopus embryo
• Vertebrate gene regulatory network

The neural crest is a transient and multipotent cell population arising at the edge of the neural plate in vertebrates. Recent findings highlight that neural crest patterning is initiated during gastrulation, i.e. earlier than classically described, in a progenitor domain named the neural border. This chapter reviews the dynamic and complex molecular interactions underlying neural border formation and neural crest emergence.

• 出版日期2012-6-1