Areca nut oil with arecoline can enhance hypolipidemia in rats

作者：Wen-hua, Zhou^*; Ai-min, Jiang; Yi-xin, P. U.; Hai-de, Zhang; Honghao, Ren

来源：Journal of Medicinal Plants Research, 2011, 5(11): 2143-2148.

• Areca nut oil
• total cholesterol
• triglyceride
• high density lipoprotein cholesterol
• arteriosclerosis index

Both Areca nut oil (OL) and arecoline play some roles in moderating hypolipidemia but the pathways may be different. The authors hypothesize OL plus arecoline can lead to an improved hypolipidemia in animal model. In this study, the fed rats with series doses of OL alone or OL plus arecoline. The gaining weight, the level of total cholesterol (TC), triacylglyceride (TG), high density lipoprotein cholesterol (HDL-C) and arteriosclerosis index (AI) from the rats were then examined. The authors found low dose of OL (0.335 g.kg(-1)) plus arecoline (3 mg.kg(-1)) could significantly reduce the level of TC and AI, and increase the level of HDL-C compared to other groups. They conclude OL (0.335 g.kg(-1)) plus arecoline (3 mg.kg(-1)) can play a synergistic role in enhancing hypolipidemia in rats.

• 出版日期2011-6-4
• 单位华南农业大学; 海南大学; 中南林业科技大学