A highly selective fluorescent probe for hypochlorite and its endogenous imaging in living cells

作者:Reja Shahi Imam; Bhalla Vandana; Sharma Anuradha; Kaur Gurcharan; Kumar Manoj*
来源:Chemical communications, 2014, 50(80): 11911-11914.
DOI:10.1039/c4cc05356g

摘要

An oxime based fluorescent probe has been designed and synthesized, which detects free as well as enzymatically generated hypochlorite with a low detection limit and high sensitivity. In addition, the probe was successfully utilized for the monitoring of endogenously produced hypochlorite in LPS stimulated cell lines, C6 glioma and BV2 microglia.

  • 出版日期2014