Determination of Bisphenol A in Food and Environmental Samples Using Combined Solid-Phase Extraction-Dispersive Liquid-Liquid Microextraction with Solidification of Floating Organic Drop Followed by HPLC

作者：Sadeghi Marzieh^*; Nematifar Ziba; Fattahi Nazir; Pirsaheb Meghdad; Shamsipur Mojtaba

来源：Food Analytical Methods, 2016, 9(6): 1814-1824.

DOI：10.1007/s12161-015-0357-6

• Dispersive liquid-liquid microextraction
• Solid-phase extraction
• Solidification of floating organic drop
• Bisphenol A (BPA)

A solid-phase extraction (SPE) coupled with dispersive liquid-liquid microextraction based on the solidification of floating organic drop (DLLME-SFO) method has been developed for extraction and determination of organic bisphenol A (BPA) in different real samples. Bisphenol A was determined by high-performance liquid chromatography-fluorescence detector (HPLC-FL). Variables affecting the performance of both steps were thoroughly investigated. The analytical characteristics of the method were determined. The calibration graph is linear in the range of 0.005-10 ng g(-1) with detection limit of 0.002 ng g(-1). The relative standard deviation (RSD) for of BPA in different samples are in the range of 6.8-9.6 % (n = 5). The obtained results show that SPE-DLLME-SFO combined with HPLC-FL is a fast and simple method for the determination of BPA in food and environmental samples.

• 出版日期2016-6