Acute effect of intermittent and continuous aerobic exercise on release of cardiac troponin T in sedentary men

作者：Ranjbar Rouhollah; Ahmadi Mohammad Amin^*; Zar Abdossaleh; Krustrup Peter

来源：International Journal of Cardiology, 2017, 236: 493-497.

DOI：10.1016/j.ijcard.2017.01.065

• Intermittent exercise
• Continuous exercise
• Cardiac troponin T
• CK-MB

Background: Studies have shown that acute exercise can increase serumconcentrations of cardiac biomarkers, including cardiac troponin T (cTnT). We investigated the acute effects of intermittent (IE) and continuous (CE) exercise at the same cardiac workload on myocardial necrosis biomarkers in sedentary men.
Methods: Eleven sedentary healthy men aged 22.3 +/- 1.9 years completed the study. The subjects were divided into two groups and performed, in random order, IE (intensity alternating between 50% (2 min) and 80% (1 min) HRreserve) or CE (60% HRreserve). The study was designed as a single-blinded randomised crossover trial performed on two distinct experimental days separated by a 1-weekwashout period. Each session consisted of 40 min of aerobic exercise, either IE or CE, on a treadmill. Blood samples were taken before (PRE), immediately after (POST) and 1 h after (POST-1) each exercise session.
Results: hs-cTnT significantly increased immediately after exercise in both protocols and remained elevated at POST-1 (P < 0.05). There was no significant difference between POST and POST-1 values(P > 0.05). Neither CE nor IE caused any significant change in CK-MB (P > 0.05). The results also showed that HR and RPP increased significantly following both exercise protocols (P=0.001).
Conclusions: In summary, both CE and IE results in increased serum concentrations of hs-cTnT in sedentary men. However, this increase does not seem to be caused by the irreversible death of cardiomyocytes. CE resulted in a greater hs-cTnT concentration than IE.

• 出版日期2017-6-1