MEROPENEM/CLAVULANATE AND LINEZOLID TREATMENT FOR EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS

作者：Dauby Nicolas; Muylle Inge; Mouchet Franc Oise; Sergysels Roger; Payen Marie Christine^*

来源：Pediatric Infectious Disease Journal, 2011, 30(9): 812-813.

DOI：10.1097/INF.0b013e3182154b05

• extensively drug-resistant tuberculosis
• meropenem
• clavulanate
• Mycobacterium tuberculosis
• linezolid

The combination of meropenem with clavulanate has high antimycobacterial activity in vitro against extensively drug-resistant Mycobacterium tuberculosis strains. We report the successful use of this combination in association with linezolid in the management of an advanced extensively drug-resistant tuberculosis disease with complex second-line drug resistance in a 14-year-old teenager.

• 出版日期2011-9