Atrial Natriuretic Peptide (ANP) in early pregnancy is associated with development of preeclampsia in type 1 diabetes

作者：Ringholm Lene^*; Pedersen Bjergaard Ulrik; Thorsteinsson Birger; Boomsma Frans; Damm Peter; Mathiesen Elisabeth R

来源：Diabetes Research and Clinical Practice, 2011, 93(3): E106-E109.

DOI：10.1016/j.diabres.2011.06.007

• Atrial Natriuretic Peptide (ANP)
• Brain Natriuretic Peptide (BNP)
• Antihypertensive therapy
• Preeclampsia
• Pregnancy
• Type 1 diabetes

The vasoactive markers of cardiac overload Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) are elevated in preeclampsia. This study documents higher ANP concentrations as early as at 9 weeks in type 1 diabetic women subsequently developing preeclampsia suggesting that preeclampsia is associated with cardiovascular changes in early pregnancy.

• 出版日期2011-9