A DEEP LEARNING SOLUTION FOR AUTOMATIC FETAL NEUROSONOGRAPHIC DIAGNOSTIC PLANE VERIFICATION USING CLINICAL STANDARD CONSTRAINTS

作者：Yaqub Mohammad^*; Kelly Brenda; Papageorghiou Aris T; Noble J Alison

来源：Ultrasound in Medicine and Biology, 2017, 43(12): 2925-2933.

DOI：10.1016/j.ultrasmedbio.2017.07.013

• Fetal ultrasound
• Neurosonography
• Pregnancy
• Trans-ventricular plane
• Convolutional neural networks
• Knowledge-based image analysis

During routine ultrasound assessment of the fetal brain for biometry estimation and detection of fetal abnormalities, accurate imaging planes must be found by sonologists following a well-defined imaging protocol or clinical standard, which can be difficult for non-experts to do well. This assessment helps provide accurate biometry estimation and the detection of possible brain abnormalities. We describe a machine-learning method to assess automatically that transventricular ultrasound images of the fetal brain have been correctly acquired and meet the required clinical standard. We propose a deep learning solution, which breaks the problem down into three stages: (i) accurate localization of the fetal brain, (ii) detection of regions that contain structures of interest and (iii) learning the acoustic patterns in the regions that enable plane verification. We evaluate the developed methodology on a large real-world clinical data set of 2-D mid-gestation fetal images. We show that the automatic verification method approaches human expert assessment.

• 出版日期2017-12