Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs

作者:Salvador Jorge A R*; Moreira Vania M; Goncalves Bruno M F; Leal Ana S; Jing Yongkui
来源:Natural Product Reports, 2012, 29(12): 1463-1479.
DOI:10.1039/c2np20060k

摘要

This review highlights the potential of natural and semisynthetic ursane-type triterpenoids as candidates for the design of multi-target bioactive compounds, with focus on their anticancer effects. A brief illustration of the biosynthesis, sources, and general biological effects of the main classes of naturally occurring pentacyclic triterpenoids (PTs) are provided.

  • 出版日期2012