Aromatic Compounds from the Liverwort Conocephalum japonicum

作者：Liu Na; Guo Dong Xiao; Wang Yan Yan; Wang Li Ning; Ji Mei; Lou Hong Xiang^*

来源：Natural Product Communications, 2011, 6(1): 49-52.

• liverworts
• Conocephalum japonicum
• monoterpenes esters
• cis-1,2-bis(3,4-dimethoxyphenyl)cyclobutane
• trans-1,2-bis(3,4-dimethoxyphenyl)cyclobutane
• cytotoxicity

Two undescribed dimeric ArC(2) derivatives, cis- and trans-1,2-bis(3,4-dimethoxyphenyl)cyclobutane (1 and 2), one new monoterpenes esters, 2 alpha,5 beta-dihydroxybornane-2-cis-cinnamate (3), along with eight known compounds, 2 alpha,5 beta-dihydroxybornane-2-trans-cinnamate (4), perrottetin E (5), isoriccardin C (6), marchantin A (7), marchantin E (8), marchantin C (9), and isomarchantin C (10) were isolated from the liverwort Conocephalum japonicum. All the structures were established by extensive spectroscopic analysis. The isolated compounds 3-10 were evaluated for their cytotoxicity against the human KB cell line with IC(50) values ranging from 16.5 to 50.2 mu M.

• 出版日期2011-1
• 单位山东大学