Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy

作者:Friborg Jeppe T; Jarrett Ruth F; Koch Anders*; Garred Peter; Freeland June M L; Andersen Andreas; Melbye Mads
来源:Clinical and Vaccine Immunology, 2010, 17(9): 1484-1487.
DOI:10.1128/CVI.00527-09

摘要

In a cohort study of children < 4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.

  • 出版日期2010-9