Association between GUC2C and ADHD: Evidence from both categorical and quantitative traits

作者：Liu, Lu; Li, Haimei; Wang, Yi; Yang, Li; Qian, Qiujin^*; Wang, Yufeng

来源：Psychiatry Research, 2014, 220(1-2): 708-710.

DOI：10.1016/j.psychres.2014.06.051

• Attention-deficit/hyperactivity disorder
• GUC2C
• Association

Guanylyl cyclase-C knock-out mice exhibit hyperactivity and attention deficits. We investigated seven single nucleotide polymorphisms (SNPs) of Guanylate cyclase 2C gene (GUC2C) in 381 ADHD trios and 382 healthy controls. Transmission disequilibrium tests (TDT), case-control studies and quantitative analyses indicated association between GUC2C with ADHD and its core symptoms.

• 出版日期2014-12-15
• 单位北京大学