A comparative screening of the catalytic activity of nanocrystalline (MZr4)-Zr-II(PO4)(6) ceramics in the one-pot synthesis of 1,6-diamino-4-aryl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile derivatives

作者：Safaei Ghomi Javad^*; Shahbazi Alavi Hossein; Ziarati Abolfazl

来源：Research on Chemical Intermediates, 2017, 43(1): 91-101.

DOI：10.1007/s11164-016-2608-6

• (MZr4)-Zr-II(PO4)(6) ceramics
• N-amino-2-pyridones
• Catalytic activity
• One pot

A four-component reaction of hydrazine hydrate, ethyl cyanoacetate, malononitrile, and aromatic aldehydes was achieved in the presence of nanocrystalline (MZr4)-Zr-II(PO4)(6) ceramics (M-II: Mn, Fe, Co, Ni, Cu, Zn, Cd) as heterogeneous catalysts to produce N-amino-2-pyridones. The reactions were performed in the presence of different catalysts, and it is observed that CdZr4(PO4)(6) nanocrystallines are the best catalysts among those examined. Atom economy, excellent yields in short times, high catalytic activity, recycling of catalyst, and environmental benignity are some of the important features of this protocol.

• 出版日期2017-1