Depressive symptoms and poor social support have a synergistic effect on event-free survival in patients with heart failure

作者：Chung Misook L^*; Lennie Terry A; Dekker Rebecca L; Wu Jia Rong; Moser Debra K

来源：Heart & Lung, 2011, 40(6): 492-501.

DOI：10.1016/j.hrtlng.2010.08.001

• Chronic Heart Failure
• Depression
• Social Support
• Outcomes

BACKGROUND: Depressive symptoms and poor social support are predictors of increased morbidity and mortality in patients with heart failure (HF). However, the combined contribution of depressive symptoms and social support event-free survival of patients with HF has not been examined.
OBJECTIVE: To compare event-free survival in 4 groups of patients with HF stratified by depressive symptoms and perceived social support (PSS).
METHOD: A total of 220 patients completed the Beck Depression Inventory-II and the Multidimensional Perceived Social Support Scale and were followed for up to 4 years to collect data on death and hospitalizations.
RESULTS: Depressive symptoms (hazard ratio = 1.73, P =.008) and PSS (hazard ratio = 1.51, P = .048) were independent predictors of event-free survival. Depressed patients with low PSS had 2.1 times higher risk of events than non-depressed patients with high PSS (P = .003).
CONCLUSION: Depressive symptoms and poor social support had a negative additive effect on event-free survival in patients with HF. Cite this article: Chung, M. L., Lennie, T. A., Dekker, R. L., Wu, J.-R., & Moser, D. K. (2011, NOVEMBER/DECEMBER). Depressive symptoms and poor social support have a synergistic effect on event-free survival in patients with heart failure. Heart & Lung, 40(6), 492-501. doi:10.1016/j.hrtlng.2010.08.001.

• 出版日期2011-12