Application of Structural DNA Nanotechnology

作者:Zhang Hong Zhi; Zhang Zhi Qing*; Wang Fang; Zhou Ting; Wang Xiu Feng; Zhang Guo Dong; Liu Ting Ting; Liu Shu Zhen
来源:Acta Physico - Chimica Sinica, 2017, 33(8): 1520-1532.
DOI:10.3866/PKU.WHXB201704271

摘要

DNA possesses extraordinary molecular recognition properties and remarkable structural features in the nano-level material regulation fields, which have shown enormous applications in many areas. In this review, we focus on DNA nanotechnology, including aspects ranging from modular DNA self-assembly to DNA origami, in addition to the recently reported novel assembly methods. Moreover, we summarize some applications of DNA nanotechnology, such as DNA-directed nanoparticle spatial positioning and orientation, and well-defined assembly of proteins on the DNA structure, as well as its uses, such as in the biomedical field, etc. The development and potential applications of DNA nanotechnology are also discussed.