Antimicrobial activity and toxicity of plants from northern Mexico

作者：Luis Benjamin Serrano Gallardo; Irais Castillo Maldonado; Claudia Guadalupe Borjon Rios; Mario Alberto Rivera Guillen; Javier Moran Martinez; Miguel Angel Tellez Lopez; Jose Javier Garcia Salcedo; David Pedroza Escobar; Maria del Carmen Vega Menchaca

来源：Indian Journal of Traditional Knowledge, 2017, 16(2): 203-207.

• Medicinal plants
• Methanol extracts
• Steers' replicator
• Antimicrobial activity

The aim of this study was to evaluate antimicrobial potential of methanolic plant extracts: Carya illinoensis (Wangenh.) K. Koch, Selaginella lepidophylla (Hook. and Grey.) Spring, Euphorbia antisyphilitica Zucc., and Jatropha dioica Sesse. Plant samples were collected from northern Mexico and the extracts were tested against reference bacteria (RS): Staphylococcus aureus (BAA44) and Klebsiella pneumoniae (9180) and clinical isolated bacteria (CB): Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli. Antimicrobial activity was performed with Steers Replicator, the LD50 was evaluated with Anemia salina bioassay, and a phytochemical screening was done with colorimetric tests. The extracts showed a minimum inhibitory concentration of 500 mu g/mL and LD50 of 1000 mu g/mL. The phytochemical tests were positive for flavonoids, lactones, quinones, triterpenes and sterols. C. illinoensis, S. lepidophillla and J. dioica had high correlations (>= 0.969) to inhibit the growth of S. aureus (RS and CB), K pneumoniae (RS) and K pneumoniae (CB) (p = 0.080, 0.076, 0.016 and 0.029, respectively). The results will contribute to the knowledge of plants used in Mexican traditional medicine.

• 出版日期2017-4