A sequential separation of linderane and norisoboldine using supercritical fluid and ionic liquid-based ultrasonic-assisted extraction from Lindera aggregate

作者：Zhou, Yifeng; Wang, Liling^*; Qin, Yuchuan; Chen, Lichun; Ge, Qing; Mao, Jianwei

来源：Separation Science and Technology (Philadelphia), 2018, 53(18): 2916-2925.

DOI：10.1080/01496395.2018.1486425

• Lindera aggregate
• linderane
• supercritical fluid extraction
• norisoboldine
• ionic liquid
• ultrasound-assisted extraction

Linderane (LDR) and norisoboldine (NOR) are two typical active compounds in Lindera aggregate (Sims.) Kosterm. In this study, a new method of sequential extraction of LDR and NOR from L. aggregate was developed by supercritical fluid extraction (SFE) and ionic liquid-based ultrasonic-assisted extraction (IL-UAE) for the first time. The suitable SFE with CO2 conditions for LDR were 60 min dynamic extraction time, 40 degrees C temperature and 30 MPa pressure. And the optimal IL-UAE factors for NOR were 2.06 mol/L 1-butyl-3-methylimidazolium bromide ([Bmim] Br) aqueous solution, 44 mL/g liquid-solid ratio, and 67 min ultrasonic time. Compared with the traditional extraction process, the sequential methods not only can obtain higher extraction efficiency, but also can realize the selective extraction for two different kinds of constituents with less consumption of traditional organic solvent. In addition, this environmentally friendly method could be used in a large-scale industry.

• 出版日期2018-12-12
• 单位浙江省林业科学研究院; 浙江科技学院