An enantioselective approach to (-)-platencin via catalytic asymmetric intramolecular cyclopropanation

作者：Hirai Sho; Nakada Masahisa^*

来源：Tetrahedron Letters, 2010, 51(38): 5076-5079.

DOI：10.1016/j.tetlet.2010.07.088

This Letter describes an enantioselective approach to (-)-platencin. A uniquely functionalized chiral intermediate, which was prepared via the highly enantioselective catalytic asymmetric intramolecular cyclopropanation (CAIMCP) that we have developed, was successfully transformed to Nicolaou's intermediate in his total synthesis of (-)-platencin.

• 出版日期2010-9-22