A near-infrared phenoxazinium-based fluorescent probe for zinc ions and its imaging in living cells

作者:Zhang, Qian-Qian; Yang, Bai-Xia; Sun, Ru; Ge, Jian-Feng*; Xu, Yu-Jie; Li, Na-Jun; Lu, Jian-Mei
来源:Sensors and Actuators B: Chemical , 2012, 171: 1001-1006.
DOI:10.1016/j.snb.2012.06.017

摘要

A phenoxazinium-based compound (1) behaving as a near-infrared (NIR) fluorescent probe toward Zn2+ was designed and synthesized. It showed selective fluorescence enhancement with the introduction of Zn2+ in buffer aqueous solution. The probe 1 exhibited distinct red fluorescence and good stability under physiological pH. In addition, fluorescence imaging experiments of Zn2+ in KB living cells demonstrated its value of practical applications in biological systems.

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