科研之友
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摘要
The West Nile region in northwestern Uganda is a focal point for human plague, which peaks in boreal autumn and is spread by fleas that travel on rodent hosts. The U.S. Centers for Disease Control and Prevention is collaborating with the National Center for Atmospheric Research to quantitatively address the linkages between climate and human plague in this region. The aim of this paper is to advance knowledge of the climatic conditions required to maintain enzootic cycles and to trigger epizootic cycles and ultimately to target limited surveillance, prevention, and control resources. A hybrid dynamical-statistical downscaling technique was applied to simulations from the Weather Research and Forecasting Model (WRF) to generate a multiyear 2-km climate dataset for modeling plague in the West Nile region. The resulting dataset resolves the spatial variability and annual cycle of temperature, humidity, and rainfall in West Nile relative to satellite-based and in situ records. Topography exerts a first-order influence on the climatic gradients in West Nile, which lies in a transition zone between the drier East African Plateau and the wetter Congo Basin, and between the unimodal rainfall regimes of the Sahel and the bimodal rainfall regimes characteristic of equatorial East Africa. The results of a companion paper in which the WRF-based climate fields were applied to develop an improved logistic regression model of human plague occurrence in West Nile are summarized, revealing robust positive associations with rainfall at the tails of the rainy season and negative associations with rainfall during a dry spell each summer.
- 出版日期2012-7
