AMBERLYST-15 CATALYZED Cbz PROTECTION OF AMINES UNDER SOLVENT-FREE CONDITIONS

作者:Bora Pranja P; Vanlaldinpuia Khiangte; Rokhum Lalthazuala; Bez Ghanashyam*
来源:Synthetic Communications, 2011, 41(18): 2674-2683.
DOI:10.1080/00397911.2010.515341

摘要

Amberlyst-15 can effectively catalyze Cbz protection of aliphatic and aromatic amines within 10-15 min under solvent-free conditions. The catalyst can be used repeatedly without loss of activity, and the reaction requires no workup and gives excellent yields.

  • 出版日期2011