A New Synthetic Method of Tetrakis(4-N,N-dimethylaminophenyl)porphyrin

作者：Sun Zhe^*; Jia Lixia; Li Yanrong; Song Jinna; Niu Guoxing

来源：Chinese Journal of Organic Chemistry, 2010, 30(4): 546-550.

• 4-(dimethylamino)benzaldehyde
• pyrrole
• dichloroacetic acid
• porphyrin

Tetrakis(4-N,N-dimethylaminophenyl)porphyrin was prepared with a new method, in which pyrrole was introduced quantificationally into the synthetic system by N(2) gas as the gas carrier under a certain rate of flow. This method can reduce the concentration of pyrrole in the reaction system effectively and restrain parts of side reactions. Finally it can improve the yield of the porphyrin as expected. The influence of reaction temperature and the amount of dichloroacetic acid which was used as a catalyst on the yield was studied. It showed that the yield of tetrakis(4-N,N-dimethylaminophenyl)porphyrin was as high as 57.0% when the reaction was carried out at 130 degrees C, and the molar ratio of 4-(dimethylamino)benzaldehyde and dichloroacetic was of 37.3. It is the highest yield in reported literatures.

• 出版日期2010-4
• 单位复旦大学