A new response-adaptive design for continuous treatment responses for phase III clinical trials

作者：Bandyopadhyay Uttam; Biswas Atanu^*; Bhattacharya Rahul

来源：Journal of Statistical Planning and Inference, 2011, 141(7): 2256-2265.

DOI：10.1016/j.jspi.2011.01.006

• Ethics
• Optimality
• Response adaptive procedure

A new response-adaptive design, applicable for general class of continuous response distributions, is proposed. The allocation design is studied both theoretically and numerically and compared with some existing procedures. The applicability of the proposed procedure is also illustrated using real life data sets.

• 出版日期2011-7