A perspective on the selection of unrelated donors and cord blood units for transplantation

作者：Spellman Stephen R; Eapen Mary; Logan Brent R; Mueller Carlheinz; Rubinstein Pablo; Setterholm Michelle I; Woolfrey Ann E; Horowitz Mary M^*; Confer Dennis L; Hurley Carolyn K

来源：Blood, 2012, 120(2): 259-265.

DOI：10.1182/blood-2012-03-379032

Selection of a suitable graft for allogeneic hematopoietic stem cell transplantation involves consideration of both donor and recipient characteristics. Of primary importance is sufficient donor-recipient HLA matching to ensure engraftment and acceptable rates of GVHD. In this Perspective, the National Marrow Donor Program and the Center for International Blood and Marrow Transplant Research provide guidelines, based on large studies correlating graft characteristics with clinical transplantation outcomes, on appropriate typing strategies and matching criteria for unrelated adult donor and cord blood graft selection. (Blood. 2012; 120(2):259-265)

• 出版日期2012-7-12