Using a Redox Modality to Connect Synthetic Biology to Electronics: Hydrogel-Based Chemo-Electro Signal Transduction for Molecular Communication

作者:Liu Yi; Tsao Chen Yu; Kim Eunkyoung; Tschirhart Tanya; Terrell Jessica L; Bentley William E; Payne Gregory F*
来源:Advanced Healthcare Materials, 2017, 6(1): 1600908.
DOI:10.1002/adhm.201600908

摘要

A hydrogel-based dual film coating is electrofabricated for transducing bio-relevant chemical information into electronical output. The outer film has a synthetic biology construct that recognizes an external molecular signal and transduces this input into the expression of an enzyme that converts redox-inactive substrate into a redox-active intermediate, which is detected through an amplification mechanism of the inner redox-capacitor film.

  • 出版日期2017-1