Near-infrared fundus autofluorescence in multiple evanescent white-dot syndrome

作者：Parodi Maurizio Battaglia; Iacono Pierluigi^*; Falcomata Bruno; Bolognesi Gianluigi; Bandello Francesco

来源：European Journal of Ophthalmology, 2015, 25(1): 43-46.

DOI：10.5301/ejo.5000534

• Blue-light fundus autofluorescence
• Multiple evanescent white-dot syndrome
• Near-infrared fundus autofluorescence
• Retro mode imaging

Purpose: To report the near-infrared fundus autofluorescence (NIR-FAF) pattern in 2 cases of multiple evanescent white-dot syndrome (MEWDS).
Methods: Three consecutive patients with MEWDS underwent a complete ophthalmologic examination, including color photograph, blue-light fundus autofluorescence, NIR-FAF, fluorescein angiography, and indocyanine green angiography (ICGA). Main outcome measure was the identification of NIR-FAF pattern.
Results: Fluorescein angiography showed patchy hyperfluorescence of the whitish dots. Indocyanine green angiography showed hypofluorescent spots throughout the examination. Blue-light fundus autofluorescence disclosed a speckled pattern without extension to the foveal area, whereas NIR-AF showed several hypoautofluorescent lesions involving also the fovea, which corresponded to the whitish dots visible on biomicroscopy and to the hypofluorescent lesions detectable on ICGA.
Conclusions: Near-infrared fundus autofluorescence is characterized by hypoautofluorescent spots corresponding to the inflammatory lesions typical of MEWDS and can be considered as a valuable noninvasive technique to diagnose and monitor patients with MEWDS.

• 出版日期2015-2