科研之友
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摘要
Purpose To calculate an optimal collimator angle at each of sectional arcs in a full-arc volumetric modulated arc therapy (VMAT) plan and evaluate dosimetric quality of these VMAT plans comparing full-arc VMAT plans with a fixed collimator angle. Methods Seventeen patients who had irregularly-shaped target in abdominal, head and neck, and chest cases were selected retrospectively. To calculate an optimal collimator angle at each of sectional arcs in VMAT, integrated MLC apertures which could cover all shapes of target determined by beam's-eye view (BEV) within angular sections were obtained for each VMAT plan. The angular sections were 40 degrees, 60 degrees, 90 degrees and 120 degrees. When the collimator settings were rotated at intervals of 2 degrees, we obtained the optimal collimator angle to minimize area size difference between the integrated MLC aperture and collimator settings with 5 mm-margins to the integrated MLC aperture. The VMAT plans with the optimal collimator angles (Colli-VMAT) were generated in the Eclipse (TM). For comparison purposes, one full-arc VMAT plans with a fixed collimator angles (Std-VMAT) were generated. The dose-volumetric parameters and total MUs were evaluated. Results The mean dose-volumetric parameters for target volume of Colli-VMAT were comparable to Std-VMAT. Colli-VMAT improved sparing of most normal organs but for brain stem, compared to Std-VMAT for all cases. There were decreasing tendencies in mean total MUs with decreasing angular section. The mean total MUs for Colli-VMAT with the angular section of 40 degrees (434 +/- 95 MU, 317 +/- 81 MU, and 371 +/- 43 MU for abdominal, head and neck, and chest cases, respectively) were lower than those for Std-VMAT (654 +/- 182 MU, 517 +/- 116 MU, and 533 +/- 25 MU, respectively). Conclusions For an irregularly-shaped target, Colli-VMAT with the angular section of 40 degrees reduced total MUs and improved sparing of normal organs, compared to Std-VMAT.
- 出版日期2017-4-6
