Phytochemical, Antioxidant and Antifungal Studies on the Constituents of Lonicera Quinquelocularis

作者：Ali Irshad^*; Khan Dilfaraz; Ali Farman; Bibi Hafsa; Malik Abdul

来源：Journal of the Chemical Society of Pakistan, 2013, 35(1): 139-143.

Seven secondary metabolites have been isolated for the first time from the chloroform soluble fraction of Lonicera quinquelocularis and identified as ferna-7, 9(11)-diene-3a, 16a-diol (1), lonicerin (log-2) (2), E-p-coumaryl hexacosonoate (3), methyl 2,4-dihydroxy-3,6-dimethylbenzoate (4), 7-hydroxycoumarin (5), secologanin dimethylacetal (6) and secologanoside-7-methyl ester (7). Their structures were elucidated by UV, IR, EI-MS, HR-EIMS, FAB, and 1 H-NMR and C-13-NMR spectral data. All of them were screened for their biological activity; compounds 3 and 5 exhibited significant antioxidant activity whereas compounds 4, 6 and 7 showed promising antifungal activity against Candida glaberata, Microsporum canis and Trichophyton longifusus.

• 出版日期2013-2