Indium(III)-catalyzed addition of diethyl acetamidomalonate to terminal alkynes: An efficient approach to beta-branched alpha-amino acids

作者：Angell Paul; Blazecka Peter G; Lovdahl Mark; Zhang Ji^*

来源：Journal of Organic Chemistry, 2007, 72(17): 6606-6609.

DOI：10.1021/jo070878+

The indium(III)-catalyzed Markovnikov addition of active methylene compounds to terminal alkynes has been expanded further to include diethyl acetamidomalonate. This reaction has been studied, and a practical approach to beta-branched a-amino acids was developed.

• 出版日期2007-8-17