NMR-based assignment of isoleucine vs. allo-isoleucine stereochemistry

作者:Anderson Zoe J; Hobson Christian; Needley Rebecca; Song Lijiang; Perryman Michael S; Kerby Paul; Fox David J
来源:Organic and Biomolecular Chemistry, 2017, 15(44): 9372-9378.
DOI:10.1039/c7ob01995e

摘要

A simple 1H and 13C NMR spectrometric analysis is demonstrated that permits differentiation of isoleucine and allo-isoleucine residues by inspection of the chemical shift and coupling constants of the signals associated with the proton and carbon at the α-stereocentre.

  • 出版日期2017-11-28