Acute Myeloid Leukemia: How Do We Measure Success?

作者:Sasine Joshua P*; Schiller Gary J
来源:Current Hematologic Malignancy Reports, 2016, 11(6): 528-536.
DOI:10.1007/s11899-016-0346-x

摘要

The development and approval of novel, effective therapies for acute myeloid leukemia (AML) has lagged behind other malignancies. Judging success of therapy with meaningful endpoints is critical to development of new treatments. Overall survival (OS) has typically been the parameter necessary for regulatory approval of experimental therapy in AML. Herein, we discuss different strategies to define outcomes for patients with AML and their relative challenges.

  • 出版日期2016-12
  • 单位UCLA