科研之友
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摘要
Background Systemic lymphoma can be difficult to recognize due to its diverse manifestations. Paraneoplastic leukoencephalopathy has rarely been reported in the context of lymphoma. Case Report We report a 45-year-old man with systemic lymphoma whose initial manifestation was sudden-onset leukoencephalopathy, mimicking stroke. This patient, who was eventually diagnosed with diffuse large B-cell lymphoma, initially presented with sudden cognitive impairment and gait disturbance. Radiological Studies Suggested a paraneoplastic leukoencephalopathy. Chemotherapy for lymphoma resulted in clinical and radiological improvement. Conclusions The presented case indicates that diffuse large B-cell lymphoma may initially appear as a treatable leukoencephalopathy. J Clin Neurol 2009;5:97-100
- 出版日期2009-6
