Process research on arylnaphthalene lignan aza-analogues: a new palladium-catalyzed benzannulation of alpha,beta-bisbenzylidenesuccinic acid derivatives

作者：Mizufune Hideya^*; Nakamura Minoru; Mitsudera Hiroyuki

来源：Tetrahedron, 2006, 62(36): 8539-8549.

DOI：10.1016/j.tet.2006.06.090

• lignans
• palladium and compounds
• naphthalenes
• biaryls

The discovery of a new Pd-catalyzed benzannulation reaction of bisbenzylidenesuccinimide during process research on arylnaphthalene lignan aza-analogues is described. An extension of the Pd-catalyzed benzannulation to the regiospecific synthesis of various arylnaphthalene lignan aza-analogues utilizing classical Stobbe condensation is included.

• 出版日期2006-9-4