Assessing the reproducibility of high definition urethral pressure profilometry and its correlation with an air-charged system

作者：Kluender Mario; Amend Bastian; Sawodny Oliver; Stenzl Arnulf; Ederer Michael; Kelp Alexandra; Sievert Karl Dietrich; Feuer Ronny

来源：Neurourology and Urodynamics, 2017, 36(5): 1292-1300.

DOI：10.1002/nau.23115

• digital signal processing
• urinary catheters
• urodynamics

IntroductionRecently, a new urodynamic method for the assessment of stress urinary incontinence called high definition urethral pressure profilometry (HD-UPP) has been introduced. This method combines a novel microtip catheter with advanced signal processing to enable spatial data location and the reconstruction of a pressure image inside the urethra. In order to assess the reproducibility of HD-UPP data, we statistically evaluate HD-UPP datasets and compare them to data from a double balloon air-charged system.
Materials and MethodsBoth catheters are used on sedated female minipigs. Data from the microtip catheter are processed through a signal reconstruction algorithm, urodynamic features are extracted, and compared to the air-charged system. Reproducibility of HD-UPP data is assessed by statistically evaluating consecutive, intra-individual datasets.
ResultsHD-UPP delivers results in agreement with previous comparisons of microtip and air-charged systems. The average deviation of two consecutive, intra-individual pressure images is very low at 7cmH(2)O.
ConclusionsHD-UPP provides physicians with detailed information on the pressure distribution inside the urethra. Through comparison with an air-charged catheter, it is shown that HD-UPP delivers results in agreement with previous studies on the comparison of microtip and air-charged catheters. It provides excellent reproducibility, as the difference between sequentially measured profiles from the same minipig is significantly lower than the one between profiles from different minipigs.

• 出版日期2017-6