Upper GI endoscopy in elderly patients: predictive factors of relevant endoscopic findings

作者：Buri Luigi; Zullo Angelo^*; Hassan Cesare; Bersani Gianluca; Anti Marcello; Bianco Maria A; Cipolletta Livio; Di Giulio Emilio; Di Matteo Giovanni; Familiari Luigi; Ficano Leonardo; Loriga Piero; Morini Sergio; Pietropaolo Vincenzo; Zambelli Alessandro; Grossi Enzo; Tessari Francesco; Intraligi Marco; Buscema Massimo

来源：Internal and Emergency Medicine, 2013, 8(2): 141-146.

DOI：10.1007/s11739-011-0598-3

• Elderly patients
• Upper endoscopy
• Peptic ulcer
• Malignancy
• Predictive factors

Elderly patients are at increased risk for peptic ulcer and cancer. Predictive factors of relevant endoscopic findings at upper endoscopy in the elderly are unknown. This was a post hoc analysis of a nationwide, endoscopic study. A total of 3,147 elderly patients were selected. Demographic, clinical, and endoscopic data were systematically collected. Relevant findings and new diagnoses of peptic ulcer and malignancy were computed. Both univariate and multivariate analyses were performed. A total of 1,559 (49.5%), 213 (6.8%), 93 (3%) relevant findings, peptic ulcers, and malignancies were detected. Peptic ulcers and malignancies were more frequent in %26gt; 85-year-old patients (OR 3.1, 95% CI = 2.0-4.7, p = 0.001). The presence of dysphagia (OR = 5.15), weight loss (OR = 4.77), persistent vomiting (OR = 3.68), anaemia (OR = 1.83), and male gender (OR = 1.9) were significantly associated with a malignancy, whilst overt bleeding (OR = 6.66), NSAIDs use (OR = 2.23), and epigastric pain (OR = 1.90) were associated with the presence of peptic ulcer. Peptic ulcer or malignancies were detected in 10% of elderly patients, supporting the use of endoscopy in this age group. Very elderly patients appear to be at higher risk of such lesions.

• 出版日期2013-3