A programmed terminal extension strategy to light up multiple beacons for DNA and cellular telomerase detection

作者：Yang, Yucai; Li, Chao; Hu, Xiaolu; Yang, Yi; Yin, Yongmei^*; Wang, Zhaoxia^*

来源：Chemical Communications, 2017, 53(42): 5752-5755.

DOI：10.1039/c7cc02515g

• SIGNAL AMPLIFICATION STRATEGY
• ROLLING CIRCLE AMPLIFICATION
• NUCLEIC-ACIDS
• ELECTROCHEMICAL APTASENSOR
• HYBRIDIZATION
• TEMPLATE
• SURFACE

Here we develop a new method for the sensitive detection of DNA and cellular telomerase using an enzyme-triggered terminal extension strategy that the produced strand can light up multiple beacons on the surface of gold nanoparticles.

• 出版日期2017-5-25
• 单位南京医科大学; 南京大学; 医药生物技术国家重点实验室