An Expanding Job Description for Bcl6

作者:Bi Enguang; Ye B Hilda*
来源:Journal of Molecular Cell Biology, 2010, 2(1): 5-7.
DOI:10.1093/jmcb/mjp032

摘要

B cell lymphoma/leukemia gene 6 (Bcl6) is well known as a master regulator of germinal center (GC) B cell differentiation. Now, three new publications demonstrate that Bcl6 also plays a second role in GC response, in that it is both required and sufficient to drive the differentiation of T follicular helper cells.

  • 出版日期2010-2