A green and convenient protocol for the synthesis of diarylmethanes via a one-pot, three-component reaction catalyzed by a novel silica tungstic acid (STA) under solvent-free conditions

作者：Shinde Vijay Vilas; Jeong Yeon Tae^*

来源：Comptes Rendus Chimie, 2015, 18(4): 449-455.

DOI：10.1016/j.crci.2014.05.010

• Silica-supported tungstic acid (STA)
• Diarylmethanes derivatives
• Friedel-Crafts reaction
• Solvent-free condition
• Multicomponent reaction

A cost-effective and eco-friendly synthesis of diarylmethanes derivatives has been developed through the Mannich type Friedel-Crafts addition reaction of tertiary aromatic amine formaldehydes with beta-naphthol/indole using silica-supported tungstic acid (STA) as a recyclable heterogeneous acid catalyst in solvent-free condition. Here, we proposed two schemes using the same catalyst. The effects of different solvents have been studied and a comparison of silica-supported tungstic acid with different acid catalysts has also been made.

• 出版日期2015-4