Abdominal Obesity is Associated With a Lower Ankle-Brachial Index in Women With Polycystic Ovary Syndrome

作者：Dogan Mustafa Inanc; Tasci Ilker^*; Bulucu Fatih; Aydogdu Aydogan; Acar Ramazan; Ceyhan Temel; Koc Bayram; Demir Orhan; Gezer Mustafa; Saglam Kenan

来源：Angiology, 2013, 64(2): 105-111.

DOI：10.1177/0003319711436248

• polycystic ovary syndrome
• ankle-brachial index
• peripheral arterial disease
• central obesity
• waist-to-hip ratio

Polycystic ovary syndrome (PCOS) was linked to increased lifetime risk of cardiovascular disease. A low ankle-brachial index (ABI) is associated with accelerated atherosclerosis. The ABI value and the associated conditions in women with PCOS were searched in the present study. The ABI was measured using a handheld Doppler device and calculated using both standard and modified definitions. Women with PCOS (n = 103, mean age = 24.9 +/- 5.9 years) had a mean ABI of 1.10 +/- 0.10. A low ABI (<= 0.9) was 2.9% and 14.6% using the standard and modified definitions, respectively. Mean ABI correlated negatively to body weight, BMI, waist circumference, waist-to-hip ratio, and hematocrit. Logistic regression analysis revealed higher waist-to-hip ratio as independently associated with a lower ABI. Frequency of ABI <= 0.9 in PCOS was lower than the general population. However, increased waist-to-hip ratio was a predictor of a lower ABI value.

• 出版日期2013-2
• 单位中国人民解放军军事医学科学院