A new platinum-bromine cyclohexanediamine complex from the family of cancer cytostatics

作者:Pazout Richard*; Maixner Jaroslav; Holakovska Jitka; Dusek Michal; Kacer Petr
来源:Acta Crystallographica Section C-Crystal Structure Communications, 2012, 68: M340-M343.
DOI:10.1107/S0108270112044770

摘要

Another new substance from the family of Pt-based coordination complexes with potential use in cancer chemotherapy has been synthesized, crystallized and structurally characterized. In this compound {systematic name cis-dibromido[(1R,2R)-cyclohexane-1,2-diamine-kappa N-2,N']platinum(II)}, cis-[PtBr2(C6H14N2)], there are two molecules with very similar conformations in the asymmetric unit. The component species interact by way of N-H center dot center dot center dot Br and C-H center dot center dot center dot Br hydrogen bonds to give two-dimensional networks which lie parallel to the (100) plane.

  • 出版日期2012-12