Access to molecular complexity via gold- and platinum-catalyzed cascade reactions

作者：Bhunia Sabyasachi; Liu Rai Shung^*

来源：Pure and Applied Chemistry, 2012, 84(8): 1749-1757.

DOI：10.1351/PAC-CON-11-09-13

• alkynes
• cascade reactions
• electrophilic activation
• gold catalysis
• catalysis
• molecular complexity
• platinum catalysis
• tandem reactions

We report recent progress on Au- and Pt-catalyzed cascade reactions to access complicated molecular frameworks. Reported reactions include new cyclization/cycloaddition cascades on carbonyl and epoxide substrates tethered with an allene, alkene, and alkyne. Such substrates enable Au-catalyzed cascade reactions comprising an initial cyclization to form reactive 1,n-dipole that undergoes subsequent cycloadditions with suitable dipolarophiles.

• 出版日期2012
• 单位清华大学