Arterial blood gas parameters in pet rabbits anaesthetized using a combination of fentanyl-fluanisone-midazolam-isoflurane

作者：Benato L^*; Chesnel M; Eatwell K; Meredith A

来源：Journal of Small Animal Practice, 2013, 54(7): 343-346.

DOI：10.1111/jsap.12081

Objectives Blood gas analysis is a well-recognized method to monitor pulmonary function, blood oxygenation, ventilation and acid-base status during general anaesthesia. The aim of this study was to report blood gas analysis results in pet rabbits (Oryctolagus cuniculus) obtained during general anaesthesia using a portable clinical analyser. Methods Thirty-two rabbits were premedicated with 0 center dot 2 mL/kg fentanyl and fluanisone. Anaesthesia was induced with 0 center dot 2 mg/kg midazolam and maintained with 2% isoflurane in oxygen via endotracheal tube. Arterial blood samples were taken from the central ear artery 10 minutes after induction of anaesthesia. Results Respiratory acidaemia was observed during anaesthesia. Mean +/- sd (range) arterial blood pH was 7 center dot 33 +/- 0 center dot 08 (7 center dot 15 to 7 center dot 48). PaCO2 and PaO2 were, respectively, 55 center dot 02 +/- 10 center dot 5 (37 center dot 7 to 92 center dot 1) mmHg and 370 center dot 0 +/- 120 center dot 5 (67 to 561) mmHg. Base excess was 2 center dot 8 +/- 3 center dot 6 (-3 to 11) mmol/L, HCO3 was 28 center dot 73 +/- 3 center dot 07 (23 center dot 7 to 35 center dot 4) mmol/L and TCO2 was 30 center dot 4 +/- 3 center dot 2 (25 to 37) mmol/L. None of the rabbits developed haematoma during arterial blood collection or ischaemia of the pinna during the hospitalization period. Clinical Significance Arterial blood gas analysis is a safe and easy to perform diagnostic technique that can contribute to improved safety of rabbit anaesthesia, by providing information on the respiratory and metabolic status of the patient.

• 出版日期2013-7