A prototype continuous-flow liquid-liquid extraction system using open-source technology

作者：O'Brien Matthew^*; Koos Peter; Browne Duncan L; Ley Steven V

来源：Organic and Biomolecular Chemistry, 2012, 10(35): 7031-7036.

DOI：10.1039/c2ob25912e

A prototype continuous-flow liquid-liquid extraction system is reported. By harnessing several open-source software libraries, a computer control script was written using the Python programming language. Using a 'computer-vision' approach, this allowed the computer to monitor the interface level between the organic and aqueous phases using a simple webcam setup and (by dynamically controlling pump flow rate) to keep this interface within defined limits. The system enabled the efficient 'inline' extraction of excess reagent in hydrazone formations, dithiane formations and epoxidations. The initial results of dispersion measurement are also presented.

• 出版日期2012