Mitotic inheritance of the Golgi complex

作者：Persico Angela; Cervigni Romina Ines; Barretta Maria Luisa; Colanzi Antonino^*

来源：FEBS LETTERS, 2009, 583(23): 3857-3862.

DOI：10.1016/j.febslet.2009.10.077

• Golgi
• Cell cycle
• Mitosis
• Membrane and organelle

In mammals, the Golgi complex is structured in the form of a continuous membranous system composed of stacks connected by tubular bridges, the "Golgi ribbon". At the onset of mitosis, the Golgi complex undergoes a multi-step fragmentation process that is required for its correct partition into the dividing cells. Regulation of Golgi fragmentation and cell cycle progression appear to be precisely coordinated. Here, we review recent studies that are revealing the fundamental mechanisms, the molecular players and the biological significance of the mitotic inheritance of the Golgi complex in mammalian cells.

• 出版日期2009-12-3